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Stem Cell Transplant in Costa Rica: Complete Guide, Costs, and What Medical Tourists Need to Know
Stem cell treatment in Costa Rica costs $3,000 to $15,000. This is 40-80% less than US prices. Clinics in San José and Escazú offer regenerative stem cell therapy (RSCT) for chronic conditions. Most treatments use mesenchymal stem cells for arthritis, autoimmune diseases, and neurological disorders.
However, there is an important difference between treatment types. Regenerative therapy differs from proven transplants used for blood cancers. This guide explains both options so you can make an informed decision.
What Is a Stem Cell Transplant?
A stem cell transplant replaces damaged cells with healthy ones. The term covers two very different treatments.
Blood-forming stem cell transplants (HSCT) treat blood cancers like leukemia and lymphoma. This proven, life-saving procedure uses high-dose chemotherapy first. Then doctors infuse new blood-forming stem cells. The process from treatment to recovery takes 14 to 18 days.
Regenerative stem cell therapy (RSCT) is what Costa Rican clinics primarily offer. This approach uses tissue repair stem cells through simple injections or infusions. There is no intensive chemotherapy involved.
Understanding this difference is crucial for setting realistic expectations:
Proven HSCT treats: Leukemia, lymphoma, multiple myeloma, aplastic anemia, sickle cell disease, and genetic blood disorders.
Experimental RSCT treats: Alzheimer’s, Parkinson’s, multiple sclerosis, diabetes, heart disease, osteoarthritis, COPD, and autoimmune disorders.
Most conditions treated at Costa Rican clinics fall into the experimental category. These treatments lack FDA approval.
Why Choose Costa Rica for Stem Cell Transplants?
Costa Rica combines quality healthcare with significant cost savings. The country ranks high in healthcare quality among Latin American nations. Physicians complete rigorous training, often studying abroad. They must register with the College of Physicians and Surgeons of Costa Rica.
Travel is convenient for North American patients. Flights from Miami take just 2.5 hours. Houston flights arrive in 3.5 hours. US, Canadian, and European citizens need no visa for stays up to 90 days.
English is widely spoken by medical staff in San José and Escazú. US dollars are accepted alongside local currency. The tropical climate and natural beauty support comfortable recovery. Nearly 2.4 million tourists visit Costa Rica each year.
For complete travel planning details, see our guide for American medical tourists in Costa Rica.
How Much Does a Stem Cell Transplant Cost in Costa Rica?
Regenerative stem cell therapy costs 40-80% less in Costa Rica than in the United States. The exact price depends on treatment type and complexity. Here is a detailed breakdown:
| Tipo de tratamiento | Costa Rica Coste | Coste en EE.UU. | Ahorro |
|---|---|---|---|
| Orthopedic (Single Joint) | $3,000 – $10,000 | $8,000 – $15,000 | 33% – 60% |
| Autoimmune/Neurological | $7,000 – $15,000 | $20,000 – $50,000+ | 60% – 80%+ |
| Anti-Aging/Wellness | $6,000 – $12,000 | $15,000 – $25,000 | 50% – 65% |
These prices are for regenerative therapy (RSCT), not blood cancer transplants. True HSCT for cancer costs hundreds of thousands of dollars. It requires intensive hospital care.
Which Hospitals and Clinics Offer Stem Cell Transplants?
The most prominent facilities are in the San José area. Most clinics are located in Escazú, an upscale suburb near the capital.
The Stem Cells Transplant Institute sits near Hospital CIMA in Escazú. Dr. Leslie Mesén is board certified in Anti-Aging and Regenerative Medicine. Cellebration Wellness holds official MINSA (Ministry of Health) certification.
Hospital CIMA was the first Latin American center with JCI accreditation. It received its sixth consecutive JCI Gold Seal in 2024.
However, no Costa Rican facility has FACT accreditation. FACT (Foundation for the Accreditation of Cellular Therapy) is required for blood cancer transplants. This matters for patients seeking standard cancer treatment.
For regenerative therapy for arthritis or chronic pain, JCI-accredited facilities may be adequate. Learn more about stem cell therapy options across Latin America.
What Are the Steps to Getting a Stem Cell Transplant?
The process begins with consultation and medical history review. Clinics may request MRI scans, CT scans, or genetic testing. They check for conditions that might make you ineligible.
Prepare your body for optimal results. Follow these simple dietary and medication guidelines starting 3 weeks before your stem
cell therapy in Costa Rica.

Costa Rican clinics require lifestyle changes before treatment. These help your body respond better to therapy:
3 Weeks Before: Cut out gluten, pork, and beef. Use only sea salt. Stop alcohol and soft drinks.
1 Week Before: Stop aspirin, ibuprofen, and NSAIDs. Stop herbal medicines and diet pills. Acetaminophen is allowed.
All Phases: No smoking is permitted.
For treatment using your own cells, clinics collect stem cells from fat tissue or bone marrow. This uses minimally invasive procedures under local anesthesia. Lab technicians then separate and prepare the cells. Doctors administer them through joint injection or IV infusion.
The recovery timeline differs greatly between treatment types:
| Fase | Costa Rica RSCT | Standard HSCT |
|---|---|---|
| Duración del procedimiento | 1-3 days outpatient | 4-8 weeks inpatient isolation |
| Immediate Recovery | 1-2 weeks soreness, rest | 2-4 weeks engraftment, high infection risk |
| Recuperación total | 6 months for improvement | 12-18 months with strict isolation |
What Types of Stem Cells Are Used?
Costa Rican clinics primarily use mesenchymal stem cells (MSCs). These are tissue repair cells valued for immune regulation and healing potential. They come from your own body or from donors.
Fat-derived stem cells are harvested from your own fat tissue. A minimally invasive liposuction procedure collects them. Since these are your cells, there is no rejection risk. Cell quality depends on your age and health. These cells can develop into bone, cartilage, heart, brain, and liver tissue.
Umbilical cord stem cells come from donated cord tissue after healthy births. Technicians collect, grow, and test these cells over three weeks. These cells are “immune privileged.” This means they work for many patients without tissue matching.
How Safe Are Stem Cell Transplants in Costa Rica?
Safety depends on which treatment type you seek. Blood cancer transplants have clear survival data from accredited facilities. Regenerative therapy has limited published evidence.
For standard HSCT at accredited centers, typical survival rates are:
| Transplant Type | 1-Year | 5-Year | 10+ Year |
|---|---|---|---|
| Using Own Cells (Autologous) | 70-80% | 60-70% | 50-60% |
| Using Donor Cells (Allogeneic) | 65-80% | 55-70% | 50-65% |
Note: No Costa Rican facility currently has FACT accreditation for complex cancer transplants.
For regenerative therapy, clinics do not publish outcomes in scientific journals. Evidence comes mainly from testimonials. This makes objective evaluation difficult.
Regenerative therapy carries specific risks:
- Infection from cell collection and injection sites
- Contamination from improperly handled donor products
- Financial loss from spending thousands on unproven treatments
- Treatment delays that harm patients with other proven options
- Unexpected complications requiring hospitalization costing $100,000+
Who Is a Good Candidate for Stem Cell Transplants?
Costa Rican clinics treat many conditions. Not everyone qualifies. Clinics review your medical history, medications, imaging, blood work, and prior treatments.
Conditions treated with regenerative therapy include:
Autoimmune and Neurological: Multiple Sclerosis, Lupus, Rheumatoid Arthritis, Alzheimer’s, Parkinson’s
Musculoskeletal: Osteoarthritis, knee injuries, Degenerative Disc Disease, Rotator Cuff injuries
Chronic Systemic: Type 1 and 2 Diabetes, COPD, Heart disease
Wellness: Anti-aging treatments, cosmetic therapies, erectile dysfunction
These are experimental uses lacking FDA approval and rigorous trial data.
Common disqualifiers include:
- Blood thinners you cannot stop
- Immunosuppressant medications
- Infecciones activas
- Diabetes no controlada
- Severe heart disease
- Inability to follow pre-treatment requirements
¿Cuánto tiempo necesito quedarme en Costa Rica?
Most patients complete regenerative treatment within one week. A typical program follows a five-day schedule in San José or Escazú:
- Day 1: Initial consultation and preparatory treatments
- Day 2: Hyperbaric chamber therapy
- Day 3: Stem cell collection and processing (for your own cells)
- Day 4-5: Stem cell administration and monitoring
Budget for a total stay of 5 to 7 days. Costa Rica’s medical tourism network accommodates family members. Many clinics partner with nearby hotels offering special rates.

What Should I Know About Choosing a Clinic?
Choosing the right clinic is your most important decision. Request detailed information before committing.
Preguntas esenciales:
- Request clinical outcome data published in scientific journals
- Demand MINSA authorization documents for your specific procedure
- Consult a specialist at a FACT-accredited institution in your home country
- Verify FACT or JACIE accreditation (required for cancer transplants)
- Check JCI hospital accreditation
Red Flags to Watch For:
- Claims that stem cells treat many unrelated diseases at once
- Advertising stem cells as a cure for dozens of conditions
- No FACT or JACIE accreditation (unacceptable for cancer treatment)
- Regenerative specialists without hematology/oncology certification
- High-pressure sales or requests for large upfront payments
Reputable clinics provide honest assessments. They acknowledge the experimental nature of RSCT. They welcome questions and set realistic expectations.
What Are the Advantages and Disadvantages of Stem Cell Treatment in Costa Rica?
Weigh the benefits against limitations before deciding.
Ventajas:
- Cost savings of 40-80% compared to US, Canada, or Europe
- High-quality general hospital infrastructure with JCI accreditation
- Easy access with short flights and no visa for 90-day stays
- English widely spoken by medical staff in San José and Escazú
- Beautiful natural environment supporting recovery
Desventajas:
Regenerative treatments lack Phase III clinical trial data. Most lack FDA approval. You are essentially participating in an unregulated experiment. There is no independent oversight or systematic follow-up.
The absence of FACT accreditation means complex cancer transplants are not available. Patients seeking leukemia or lymphoma treatment should exercise caution.
Standard insurance does not cover experimental treatments. You pay all costs yourself. If complications arise, critical care could exceed $100,000. This would eliminate your initial savings.
Is Costa Rica the Right Choice for Your Stem Cell Transplant?
Costa Rica offers affordable regenerative stem cell therapy with quality hospital infrastructure. It may suit you if you seek experimental treatment for chronic conditions. You should have exhausted conventional options. You must understand the experimental nature. You need the ability to afford costs without insurance.
For standard blood cancer transplants (HSCT), Costa Rica is not appropriate. The required FACT/JACIE accreditation does not exist in the private sector. For leukemia or lymphoma, seek treatment at accredited facilities in your home country. You can also explore stem cell transplants in Colombia for additional Latin American options.
Before deciding:
- Consult your home country specialist
- Confirm you understand these treatments lack FDA approval
- Verify you can afford complete financial loss
- Confirm you have tried evidence-based therapies first
Costa Rica works for experimental RSCT if you have realistic expectations. It is not appropriate for cancer transplants or patients who cannot afford complications.
Frequently Asked Questions About Stem Cell Treatment in Costa Rica
How long do stem cell therapy results last in Costa Rica?
Results vary by condition and individual response. Many patients report improvements lasting 1–3 years, but some conditions require repeat treatments. Clinics cannot guarantee outcomes because these therapies are experimental.
Is stem cell treatment in Costa Rica painful?
Most patients report minimal pain. Fat-tissue collection uses local anesthesia; you may feel soreness at injection sites for a few days. IV infusions are generally painless. Recovery discomfort is usually mild compared to surgery.
Can I travel alone for stem cell treatment in Costa Rica?
Yes, but a companion is recommended. You may feel tired after procedures, and having help with meals and transportation reduces stress. Many clinics can arrange a medical escort if you travel alone.
Are stem cell clinics in Costa Rica legitimate?
Legitimate clinics carry certification from Costa Rica’s Ministry of Health (MINSA). Look for hospital JCI accreditation, verify physician credentials, and ask for published outcomes. Avoid clinics promising “miracle cures” or pressuring quick payment.
Does insurance cover stem cell treatment in Costa Rica?
Most insurance plans do not cover experimental stem cell therapy, so you will likely pay out of pocket. Some clinics offer payment plans. Budget for the full cost, travel, and potential complications before committing.
What happens if stem cell treatment in Costa Rica doesn’t work?
Refunds are uncommon for unsuccessful outcomes, and you assume the financial risk. If complications arise, additional medical costs may apply. Discuss realistic expectations in writing with your clinic and consider a second opinion from your home-country physician.
What conditions are commonly treated with stem cells in Costa Rica?
Clinics often target osteoarthritis and sports injuries, some spinal and disc issues, certain autoimmune disorders, and select neurological conditions. Evidence is still emerging, and effectiveness varies by diagnosis and patient factors.
What types of stem cells do clinics in Costa Rica use?
Most programs use mesenchymal stem/stromal cells (MSCs) sourced from your own fat or bone marrow, or allogeneic cells from screened umbilical cord tissue. Embryonic stem cells are generally not used. Confirm sourcing, screening, and consent documents before treatment.
How much does stem cell therapy in Costa Rica cost?
Prices vary widely by clinic, cell source, dose, number of injections/IVs, and add-ons (imaging, rehab, accommodations). Expect costs from several thousand to tens of thousands of USD. Request an itemized quote and a total travel budget before booking.
What are the risks and side effects of stem cell treatment?
Common effects include injection-site soreness, fatigue, or headache. Less commonly, infection, bleeding, allergic or immune reactions, or clotting can occur. Long-term benefits and risks are still being studied. A full medical evaluation and informed consent are essential.
How long should I stay in Costa Rica and what aftercare is needed?
Many programs schedule evaluation, cell collection, and infusion over several days. Plan a flexible stay of about 3–7 days, follow activity and medication guidance from your clinic, and arrange virtual follow-ups once you return home.
Ready to Start Your Stem Cell Treatment Journey?
Medical Tourism Packages coordinates your entire stem cell treatment journey in Costa Rica. We connect you with certified regenerative medicine specialists in San José and Escazú. We arrange your travel and accommodations. We provide bilingual support throughout your treatment. Get a free consultation to discuss your health goals and receive a personalized quote.
Contact us today to start planning your affordable stem cell treatment in Costa Rica.



